Heat shock transcription factor(HSF)-1 activates the transcriptional activity of heat shock genes through ( )
选项：

A:effect of heat shock transcription factor monomer protein;
B:effect of heat shock transcription factor dimer;
C:effect of heat shock transcription factor trimer;
D: effect of denatured protein combined with heat shock factor trimer;
E:binding of denatured protein with monomer heat shock factor